Thousands of BRCA1 and BRCA2 mutations on relevant are likely to increase the risk of women suffering from cancer. However, it is difficult to say whether these mutations would make someone suffering from cancer, because researchers did not have enough evidence of Mouse Estradiol ELISA Kit http://www.cusabio.com/ELISA-Kit/Mouse-EstradiolE2-ELISA-Kit-75683.html impact is indeed statistically founded.
These mutations are called mystical variant of unknown significance. And people feel they are a headache - because it is hard to determine whether a person needs to take action, for example, preventive surgery. People may not realize that some laboratories are more likely than the other laboratories found that the latter was unable to explain the significance of the mutation.
Over the years, Salt Lake City, Utah, the company has a monopoly Liard gene BRCA gene test the United States. 2013, the US Supreme Court's ruling allows other companies can conduct such tests, but the company still has more Liard gene mutation on how to improve the risk of cancer data than any other company in the world. Therefore, the researchers estimate that the company reported unknown significance variant is only 2-3%, compared to tests conducted by other companies will find that 10% of the variants of unknown significance.
Geneticists are trying to set up a public database, which the company competes with Liard gene, BRCA mutations and to understand the implication of more significance. When they do so, the researchers found that some mutations affecting virtually unknown and there is no harm to the human body.
For example, because most studies tend to focus on human cancer genes have European ancestry who, so there is still a fair chance that an African-American man suffering from cancer may carry an unprecedented mutation. This single observation suggests that the variation will increase the risk of cancer. But as time goes on, more data about the African-American can be shown that the initial data point is just a fluke, but the mutation does not increase the risk of cancer.
