Recent Entries

• Creative Proteomics Provides Advanced Cell Invasion Assay Servi

  by chen shanshan Feb 28
  Creative Proteomics, an integrated company that provide various biotechnology services to researchers in pharmaceutical, biotechnology, and academic and government organizations, has recently launched its fully-developed cell invasion assay services, which help study the molecular processes of these...

• Learn New Metal-Organic Frameworks Materials Findings in Ten Mi

  by chen shanshan Feb 26
  Metal-organic frameworks (MOFs) are materials that are made up of a regular array of positively charged metal ions surrounded by organic 'linker' molecules. They are organic/inorganic hybrid porous crystalline. Compared with other porous materials, MOFs provides a uniqu...

• Introduction to Three Types of Cell Culture

  by chen shanshan Feb 24
  Cell culture refers to a method that simulates the internal environment (sterile, appropriate temperature, pH, and certain nutritional conditions, etc.) in vitro to make it survive, grow, reproduce and maintain its main structure and function. There are three types of cell culture. Animal cell c...

• The Relationship Between Probiotics and Human Health

  by chen shanshan Feb 23
  At present, people have a deep understanding of the importance of macro-ecological balance, but micro-ecological balance is far from receiving the attention it deserves. Understanding the importance of the micro-ecological balance of the human body and maintaining the micro-ecological balance can en...

• BOC Sciences Launched A New Enzyme Labeling Platform

  by chen shanshan Feb 22
  Recently, BOC Sciences, a well-known chemical and pharmaceutical supplier, announced the launch of a new enzyme labeling technology platform for the scientific community. Enzyme labeling is a method to place chemical markers on the molecules of substances in bioanalysis. Mol...

• Nature: Eight Proteins Transform Mouse Stem Cells into Oocyte-l

  by chen shanshan Feb 21
  A combination of eight proteins can transform mouse stem cells into cells that look much like immature eggs, oocytes. The resulting ovomatrix-like cells cannot undergo meiosis, but can be fertilized by sperm and then divide until they reach the eight-cell stage of embryonic development, the research...

• Creative Biolabs Supplies Multiple Tetramer Products for Immuno

  by chen shanshan Feb 20
  As a specialized solution provider in the field of biotechnology, Creative Biolabs delivers standard biotech products to global clients as a support of their projects or studies of various purposes, which are produced with the help of high-end productive platforms and sophisticated technologies. Reg...

• Creative Biolabs' "Magic" Platform Promotes Multifunctional Mem

  by chen shanshan Feb 19
  Membrane proteins on the cell surface stimulate various biological pathways and regulate important cellular functions, such as cell interaction, material transport, energy conversion, information reception, recognition, and transmission. Many abnormal expressions of membrane proteins were repor...

• CHIRAL CATALYSTS ARE NEWLY RELEASED AT ALFA CHEMISTRY CATALYSTS

  by chen shanshan Feb 18
  As the research on chiral drugs, chiral pesticides and chiral materials continues to be deepened, the demand for optically pure chiral compounds has increased dramatically. To better meet the increasing need arising from the development of chiral synthetic chemistry, the specialized branch of the wo...

• Virus Sequencing: Technologies, Features, and Significance in O

  by chen shanshan Feb 1
  Emerging infectious diseases have the potential to impose enormous mortality, morbidity, and economic burdens on humans. Tracking the spread of infectious diseases to help control them has traditionally relied on the analysis of case data collected during the course of an epidemic or pandemic. Over ...

• Magnetic Beads (MBs) for Magnetic Resonance Imaging

  by chen shanshan Jan 31
  Magnetic resonance imaging (MRI) is considered to be one of the most powerful techniques in diagnostics, clinical medicine and biomedical research. In MRI, the contrast agents are the key point because if without them, biological and functionally informative images cannot be obtained....

• An Overview of Biomarkers (I)

  by chen shanshan Jan 29
  Before being used in the field of biomedicine, the term "Biomarker" was more common in geological literature. It was once translated as "biomarker compound", which refers to some organic compounds in geological materials derived from living organisms. In the 1960s, this term began to appear in med...

• Application of artificial intelligence in drug development

  by chen shanshan Jan 28
  Through machine learning, evolutionary computing, image recognition, natural language processing and cognitive computing, artificial intelligence (AI) can be applied in the following fields: Drug Targets Development, Drug Mining, Compound Screening, Predication of ADMET Properties, Crystal Structure...

• Exploring the way of plant disease resistance: major discoverie

  by chen shanshan Jan 27
  Plants are the basis for human survival. They convert solar energy into chemical energy through photosynthesis and produce the oxygen we need. However, plants also face various threats and are attacked by phytopathogens such as viruses and bacteria, leading to illness or even death. Statistics show ...

• What Everybody Ought To Know About Fluorescent Polymers

  by chen shanshan Jan 26
  In recent years, there are huge demands for fluorescent materials, as they play important roles in various research areas such as chemistry and biology. Due to their fascinating properties and important applications in the fields of materials and life sciences, the research on fluorescent polymers&n...

• Novel Therapies of Protein Degradation Represented by PROTAC

  by chen shanshan Jan 24
  An important method for cells to regulate their internal protein concentration is through the Ubiquitin/Proteasome system (UPS) that connects the ubiquitinase to the target protein through a complex protein system, and then the proteasome recognizes the ubiquitinase to find the target prot...

• The Important Role of in Vitro Screening Related Services in Dr

  by chen shanshan Jan 16
  In VitroScreening is a screening process used to find a small number of compounds with the desired biological activity in a large collection. The basic premise of screening is that biological assays are repeatable, reliable, robust and biologically relevant.Creative Bioarray provides a range of prod...

• Main Applications of Polyethylene Glycol (PEG) (Part Two)

  by chen shanshan Jan 2
  Biological uses PEG can be modified and crosslinked into a hydrogel and used to mimic the extracellular matrix (ECM) environment for cell encapsulation and studies. An example study was done using PEG-Diacrylate hydrogels to recreate vascular environments with the encapsulation of endothe...

• JOINTLY DISCOVER OPTIMAL PROTAC MOLECULES WITH CREATIVE BIOLABS

  by chen shanshan Jan 1
  The achievement by far of PROTAC based drugs can never be separated from the discovery of how cells clean up abnormal proteins, i.e., the protein degradation process regulated by Ubiquitin, which was awarded the Nobel Prize in Chemistry in 2004. PROTAC drug, as a novel therapeutic method with great ...

• Creative Biolabs Optimizes One-stop Complement Therapeutics Ser

  by chen shanshan December 31, 2020
  With more and more research focusing on complement system, the development of complement-directed drug discovery has achieved success. And as a first-class biotech manufacturer, Creative Biolabs has updated its one-stop complement therapeutics services. Complement therapeutics have bright prospects...

• A Study about New affinity purification technique for therapeut

  by chen shanshan December 30, 2020
  Professor Kimoon Kim's research group at POSTECH has developed a highly pure and efficient technique for purifying antiviral and anti-cancer protein therapeutics using molecular affinity interaction. With COVID-19 showing no signs of slowing down around the world, the development of a vaccine seems...

• Studying DNA-protein interactions? You Must Know These Techniqu

  by chen shanshan December 27, 2020
  In many cellular life activities, such as DNA replication, mRNA transcription and modification and viral infection, the interaction between DNA and proteins is involved. In the past half century, predecessors have carried out a lot of exploration in the composition and decomposition proces...

• Brief Introduction about the Recent Progress in Structural Biol

  by chen shanshan December 25, 2020
  Structural biology is a branch of molecular biology, biochemistry, and biophysics concerned with the molecular structure of biological macromolecules how they acquire the structures they have, and how alterations in their structures affect their function. (Wikipedia) This post is a roundup blog tel...

• Creative Biostructure Provides De Novo Design for Protein Engin

  by chen shanshan December 25, 2020
  Scientists in the field of protein engineering and analysis now have access to the newly updated de novo protein design service, an attractive approach for constructing designed proteins with predetermined structures and functions. The process of protein molecular design mainly relie...

• 4 Hot Whitening Ingredients You Will Find in Skincare Products

  by chen shanshan December 17, 2020
  Abstract: Every culture has its take on what is beautiful. Some find sun-kissed skin attractive, while some prefer lighter skin. Thus skincare products with whitening function are popular in some area. So how to select a suitable one among the numerous products? Exposure to sun, wounds, rashes,etc....

• The Usage and Precautions of Adalimumab

  by chen shanshan December 14, 2020
  Adalimumab (Humira) is a self-injectable biotherapeutic drug. It has been approved by the China Food and Drug Administration (CFDA) for 2 indications, namely rheumatoid arthritis and ankylosing spine inflammation. In 2013, through the study of adverse events in clinical trials of adalimumab for var...

• BOC Sciences Launches Novel, Cost-Effective Impurities Synthesi

  by chen shanshan November 30, 2020
  BOC Sciences, a leading global supplier and manufacturer of premium chemicals, has recently announced the launch of impurities synthesis for API development, expanding its custom synthesis service portfolio. SHIRLEY, NY - Mar 21, 2019 - BOC Sciences, a US-based global supplier of cost-effective che...

• What Is Food Composition Analysis?

  by chen shanshan November 25, 2020
  Food composition analysis refers to the analysis of substances that can sustain life and development, that is, provide energy and form or replace tissues. However, it is more difficult to use this food definition for industry management. Therefore, many countries and regions have formulated their...

• Creative Proteomics Provides Various Chemical Composition Analy

  by chen shanshan November 24, 2020
  SHIRLEY, NY - Sep14, 2020 -Creative Proteomics, an integrated CRO company committed to providing proteomics and metabolomics services, has recently optimized a serious of chemical composition analysis services. The services are based on a mature and reliable experimental analysis platform....

• Creative Diagnostics Releases Prealbumin Antigen and Antibody P

  by chen shanshan November 23, 2020
  Abstract: With more than 15 years’ experience in the biopharmaceutical market, Creative Diagnostics now unveils its new products, native prealbumin/TTR antigens and monoclonal antibodies to worldwide clients. Prealbumin is synthesized in the liver and then released into circulation prior...

• Bacterial Intracellular Biomineralization Can Form Magnetic Nan

  by chen shanshan November 20, 2020
  In 1963, Italian scholar Bellini first discovered susceptibility bacteria in freshwater and published research results, but they did not attract attention. In 1975, when an American doctor of microbiology studied spirochetes in seafloor sludge, he accidentally found that this type of microorganism t...

• An Overview of Researches on Targeted Protein Degradation (III)

  by chen shanshan November 19, 2020
  4 Application of PROTAC technology in biomedicine PROTAC technology has made a series of progress in the field of biomedical research: 4.1 For tumor treatment The formation of most tumors is related to the abnormal expression of key intracellular proteins. The knockout of proteins related to...

• ADC Ushers in R&D Fever: Merck's US$4.2 Billion Investment

  by chen shanshan November 18, 2020
  Big Announcement On September 15, 2020, Seattle Genetics and Merck & Co jointly announced two strategic collaboration projects of oncology, including a $4.2 billion partnership for the new ADC drug ladiratuzumab vedotin. ADC (Antibody-drug conjugate) is a complex formed by covalently cou...

• Introduction to Virus Infections and Common Viruses

  by chen shanshan November 14, 2020
  Viruses are small infectious agents that carry genetic material, RNA or DNA. They are surrounded by a layer of proteins, lipids or glycoproteins. They replicate in the cells of another organism, so they are parasitic. Humans, animals, plants and microorganisms can all be infected by viruses....

• Research Progress about Amyotrophic Lateral Sclerosis and Treat

  by chen shanshan November 12, 2020
  Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease; so far, there is no effective treatment. Recently, Professor Martinez from the Biological Research Center in Spain, in the Expert Opin Investig Drugs magazine, combed the status of clinical treatment of ALS and more than 20 potenti...

• What is Artificial Intelligence?

  by chen shanshan November 3, 2020
  Artificial intelligence (AI) has the potential to transform the pharmaceutical industry. There are a growing number of applications that address target and drug discovery, preclinical and clinical development, and post-approval activities using AI technologies. The use of AI in life sciences, especi...

• Small Molecule Peptide Inhibitors and Alzheimer's Disease

  by chen shanshan November 2, 2020
  Alzheimer's disease is a typical neurodegenerative disease. Clinically, mental impairment is the main cause, including memory loss, language ability, spatial discrimination ability and cognitive decline (for an introduction to Alzheimer's disease, please refer to this column "The Eraser of Memory")....

• An Overview of Lymphocyte Proliferation Test

  by chen shanshan November 1, 2020
  This test can detect whether the nano silver material can induce lymphocyte proliferation or inhibit the lymphocyte proliferation response induced by phytohemaglutinin (PHA-M). Lymphocytes can be separated from the mixed heparin anticoagulated whole blood using Ficoll-Paque separation solution. Afte...

• Nano Revolution Is Coming—Sometimes, Smaller Is Better

  by chen shanshan October 27, 2020
  Abstract: In recent years, nanotechnology frequently appears in the media, and the superiority of nanotechnology, nanomaterials, and products made with nanotechnology are also widely promoted. So, what exactly are nanotechnology and nanomaterials?   The word “nano” comes...

• The application of PROTACs targeted protein degradation in drug

  by chen shanshan October 26, 2020
  The occurrence and development of many diseases are related to the abnormal expression of the target protein. Regulating the expression of the target protein is not only related to research fields such as biology and medicine, but is also of great significance for the development of new drugs. Since...

• Standard or Custom Therapeutic Glycoprotein Services Are Availa

  by chen shanshan October 24, 2020
  Abstract: Based on the comprehensive and advanced technical platform, Creative Biolabs has updated its one-stop therapeutic glycoprotein services to promote project success of global clients.   Glycoproteins play a key part in important cellular functions like embryonic develop...

• Bispecific Antibody: A Rising Star in Cancer Immunotherapy

  by chen shanshan October 23, 2020
  Abstract: Bispecific antibody research and development has received industry attention in recent years. These antibodies can bind to two antigens at the same time, thus being able to explore therapeutic opportunities that monospecific antibodies cannot reach.   Cancer immunotherapy has m...

• CD Genomics Announces MicroCollect™ FDA&CE Certificated Virus C

  by chen shanshan October 6, 2020
  SHIRLEY, NY – Jul 10, 2020 - CD Genomics, an internationally leading provider of microbial testing services, microbial genomics services, and integrated bioinformatics services for hospitals, food, diagnostics, pharma, agriculture, biotechnology, and research institutes, announces advance...

• The Principle of Biotinylated Protein

  by chen shanshan October 4, 2020
  Because the molecular weight of biotin is not large (molecular weight is 244.31), the biotinylation reaction is fast, efficient and not easily interfered. Biotinylated molecules can interact with streptavidin and avidin through biotin, and are not affected by high heat, pH, and proteolysis. The co...

• Types of Chemical Battery (I)

  by chen shanshan October 3, 2020
  A chemical battery refers to a device that can convert chemical energy into electrical energy. The main part includes the electrolyte solution and the positive and negative electrodes immersed in the solution. When in use, the wire is connected to the two electrodes, that is, current flows (discha...

• What Is the Third-generation Sequencing

  by chen shanshan September 27, 2020
  The third-generation sequencing technology is a milestone. Marked by PacBio's SMRT and Oxford Nanopore Technologies' nanopore single-molecule sequencing technology, it is called the third-generation sequencing technology. Compared with the previous two generations, the biggest feature is single-mo...

• ADCs: Conjugation Methods of Linker and Antibody

  by chen shanshan September 21, 2020
  Nevertheless, scientists have not given up this highly potential technology. After Mylotarg, four ADCs drugs have been approved by the FDA. They are Adcetris (brentuximab vedotin, jointly developed by Takeda/Seattle Genetics, in 2011, for the treatment of Hodgkin’s lymphoma and systemi...

• Lysosomal targeted chimeras degrade extracellular proteins

  by chen shanshan September 19, 2020
  When scientists discover potentially dangerous proteins on cells, they may imagine shrinking themselves as small surgeons, removing only problematic protein molecules and leaving the healthy cells. In a new study, researchers from Stanford University point out that although dexterous hands and ...