Recent Entries

  • What is morphology analysis

    Morphology analysis refers to the role of specific elemental morphology in the system. It is a method of separating elemental morphology based on its chemical form and other forms of the same element that may exist. It is defined using physical or chemical methods that separate a specific group of m...
  • Rapid tests technology for food safety assurance (Part Two)

    (5). Additive testing: Additives generally refer to compounding materials or auxiliary materials to improve the quality, performance and use effect of chemical products, which are added to the main raw materials of the product to improve product performance. Mainly used in printing and dye...
  • Creative Biolabs Announced cd25 Monoclonal Antibody for Researc

    November 19, 2019, as a leading supplier in the recombinant antibody field, Creative Biolabs aims to provide high-quality services and products to clients in the academia and industry fields all over the world. Recently, Creative Biolabs released cd25 monoclonal antibody for research use. This produ...
  • The Clinical Applications of Methotrexate

    Methotrexate (MTX) is a kind of folic acid antagonists, which belongs to metabolic antitumor drugs. The methotrexate mechanism of action is to inhibit dihydrofolate reductase from transforming into tetrahydrofolate, so as to interfere with DNA synthesis and prevent tumor cells from pr...
  • Where do antibodies come from?

    Hi Everyone, I am sure that you have already heard a lot about antibodies throughout all our blogs and by now you most probably have an idea of what they are, how they work and why they are such a key element of our immunoassays. But have you also wondered about the fact where these antibodies actu...
  • Biomarkers for In Vitro Diagnostics (Part Two)

    Complex biomarkers Complex biomarkers include certain DNA called molecular adducts and proteins. Small molecule adducts, DNA-protein complexes, and protein-protein complexes can be used to indicate disease. Telomeres are a DNA-protein complex that is present at the end of a chromosome in a euk...
  • Some Research and Analytical Methods on Protein

    Amino acid analysis Amino acid analysis is a method used to determine the amino acid composition or content of proteins, peptides and other pharmaceutical preparations by physical and chemical means. Protein and peptide can be identified according to the composition analysis of amino acids. Am...
  • New In Situ Protein Mass Spectrometry Based on Nanosecond Photo

    At present, proteomics and related quantitative techniques based on bio-mass spectrometry are experiencing rapid development. However, protein identification and protein structure analysis at this stage often need to be performed separately using different analysis platforms. This not only reduces t...
  • Creative Proteomics Provide Glycosylation Service for Lab Resea

    Since its establishment in 2004, Creative Proteomics has gradually been a leading supplier providing proteomics, glycomics, metabolomics and bioinformatics analysis services. And it has enjoyed a good fame among customers and clients from different fields, including industry, clinical research, acad...
  • Reviews on the research progress of PD-1/PD-L1 inhibitors for t

    The general Triple-negative breast cancer (TNBC) refers to breast cancer with negative expression of human epidermal growth factor receptor-type 2 (Her-2), estrogen receptor (ER) and progesterone receptor (PR). TP53 deletion and somatic cell copy number mutation are common...
  • Unequivocal Discrimination of Leucine & Isoleucine

    Creative Biolabs Achieved an Unparalleled Breakthrough in De Novo Antibody Sequencing Creative Biolabs, a dynamic biotech company engaged in customized antibody development for decades, announced that the precise identification of leucine and isoleucine by mass spectrometry has been unprecedentedly...
  • Why people ignore pesticide residues and how it affects us?

    Pesticide residues seem to be inevitable for most people and they think it’s not a big deal since they have been eating for decades. Why are they so careless about pesticide residues? Is it really not dangerous? Does the current pesticide residue standard safe enough? ...
  • Human and Animal Brucella and Clinical Infections (section one)

    Brucellosis is a systemic disease affecting various organs or body systems and simulating other diseases. Symptoms are nonspecific, which generally include fever, sweating, malaise, headache, back pain, loss of appetite. Symptoms can develop suddenly, evenly or over a week period. Involvement o...
  • The Introduction of TCR Signaling Pathways

    T-cell-related immunotherapy has shown great promise in recent cancer research. The main force is CAR-T and TCR-T technologies. Compared with CAR-T cell therapy, TCR-T therapy attracts less attention, but both of them belong to the frontier gene therapy for cancer using patients' own T lym...
  • Something About Dasatinib that You May not Know

    Dasatinib, alias DASA Tin IB, is a gray to yellow solid chemical. Dasatinib is an anti-tumor drug that is clinically the primary treatment for imatinib mesylate-resistant, or intolerant adult chromosomes of chronic chromosome-positive chronic myeloid leukemia in the chronic phase, accelerated phase,...
  • Introduction, application and development of spectroscopy

    Electromagnetic waves are generated by electrons moving inside the atom. Since the movement of electrons inside the atoms of each substance is different, they emit different waves. Studying the luminescence and absorbing light of different substances has important theoretical and practical sign...
  • Introduction to several protein engineering methods

    Based on the dynamics and protein chemistry, protein crystallography study, protein engineering obtain information about the physical and chemical properties and molecular properties of protein, rational protein design, through protein three-dimensional mechanism, function and mechanism of detailed ...
  • iTraq&TMT Labeling Technology

    Quantitative Proteomics is the accurate identification and quantification of all proteins expressed in a genome or all proteins in a complex mixed system. It can be used to screen and find differentially expressed proteins between samples caused by any factor, combined with bioinformatics to re...
  • A list of single cell sequencing applications and research resu

    Science: single-cell RNA sequencingreveals the composition of two brain cancers A careful analysis of the two brain cancers revealed that the two brain cancers were derived from the same type of neural precursor cells and could be distinguished by genetic mutation patterns and microenvironmenta...
  • Creative Enzymes Enzymology Assays: All Types of Enzymology Ass

    Creative Enzymes, a world’s leading biotechnology producer and a renowned services provider has recently announced the release of Enzymology Assays, supporting lab research as well as industrial production. Based on the resources that are required for the task, we provide mainly four kinds of ...
  • Creative Biolabs: A Pioneer in Antibody-drug Conjugate Field

    Creative Biolabs, an international cooperation located in New York, USA, has devoted itself in advanced antibody biochemistry and engineering for over 10 years. Supported by rich experienced scientists and technicians, Creative Biolabs has established the leadership in targeted immunotherapy and&nbs...
  • Classification of Adipokines by Functions and Affections

    The adipokines, also adipocytokines, are now widely accepted to be cytokines (cell signaling proteins), acute phase reactants, growth factors, other inflammatory mediators, hormones secreted by adipose tissue. Many of them are proteins, protein hormones, or genetic substances existing in the body ce...
  • Talking about Membrane Protein and Its Production

    Membrane proteins are proteins in biological membranes. They account for over 30% of all proteins in human genome and are responsible for primary cellular functions, including materials transportation, signal transduction, intercellular recognition ligand-receptor binding, and cell ad...
  • Vadastuximab Talirine: The Third Generation of Antibody-drug Co

    Antibody-drug conjugates (ADCs) drugs are composed of antibodies (linkers) combined with cytotoxic drugs (Payload). After the drug binds to the target, the cells are endocytosed, and the cytotoxic drugs are usually released in the lysosome to kill the tumor cells. Due to the strong antibody targetin...
  • Protein binding and immunoassay

    The synthesis of Protein production is also known as translation, which is the process of converting the sequence of the bases in the mRNA molecule into the sequence of amino acids in the egg or polypeptide chain, which is the second step of Protein Expression and the final Protein synthesis se...
  • Will CGRP Antibodies Be a Blockbuster for Migraine Treatment?

    CGRP is a 37 amino acid neuropeptide secreted by the nervous system of the central nervous system and the peripheral nervous system. It is widely distributed in the sensory nerves of the peripheral nervous system and the central nervous system and exhibits a large number of different biological acti...
  • Classification and Introduction of Viral antigens Part II

    Canine distemper virus Canine distemper virus (CDV) is a non-segmented single RNA measles virus that belongs to the family Paramyxoviridae. CDV is a causative agent of severe systemic disease with fever, immunosuppression, pneumonia, enteritis. The CDV is large, 150-250 nm in diameter, a...
  • The Introduction of Immunotoxin

    What is immunotoxin? Malignant tumors are a kind of serious diseases that endanger human health. With the deterioration of human living environment and the increase of social pressure, the incidence and mortality of malignant tumors are gradually increasing. Surgery is the main treatment ...
  • Introduction to vaccine types and differences (part two)

    Live-attenuated vaccine This type of viral vaccine has more than 90% efficacy and its protection usually lasts for many years. Its outstanding advantage is that the pathogen produces an antigenic stimulus in the host replication, the amount, nature and location of the antigen are similar to th...
  • Introduction to Tumor Immunotherapy—Part One

    Under normal circumstances, the immune system can identify and remove tumor cells in the tumor microenvironment, but in order to survive and grow, tumor cells can adopt different strategies to inhibit the body's immune system, unable to kill tumor cells normally, called immune escape. In order to be...
  • The new chapter in tumor immunotherapy—immunological checkpoint

    Because of its significant survival benefit, tumor immunotherapy has become a new effective treatment option for cancer followed by surgery, chemotherapy, radiotherapy and targeted therapy. As one of the methods for tumors, immunological checkpoint inhibitors have been approved for the treatment of ...
  • Some Key Genes You Should Know About Cancer

    Genes are all the nucleotide sequences needed to produce a polypeptide chain or functional RNA. Genes support the basic structure and performance of life, and store all the information of life's race, blood type, gestation, growth, apoptosis and other processes. The interdependence of environment an...
  • New Treatment for Skin Cancer - Skin Cancer Vaccine (Part Two)

    Melanoma Melanoma is the most aggressive malignant tumor in skin cancer. In the past 20 years, the incidence rate worldwide has risen sharply, increasing at a rate of 3.1% per year. The incidence rate in China is relatively low, but in recent years, the growth has accelerated, with about 20,000...
  • Immunotherapy for tumors (Section One)

    Unlike previous surgical excision, chemotherapy, radiotherapy and gene targeted therapy, cancer immunotherapy is aimed at a patient own immune system to fight cancer. In recent years, monoclonal antibodies against immune checkpoints have created a revolution in clinical oncology, ...
  • An overview of new progress in stem cell culture manufacturing

    Nature Materials: "squeezing" cells into stem cells DOI: 10.1038/nmat4536 Scientists at the EPFL in Lausanne, Switzerland, have recently developed a new method to help cells become available stem cells. This approach involves the use of gels to "squeeze" cells, paving the way for large-scale p...
  • The Increasingly Important Role of Lentivirus Packaging

    Abstract: Recently, studies indicate that many diseases like tumors, are closely related to genetic abnormalities. As a result, gene therapy has become a crucial way of clinical treatment of diseases. In order to achieve efficient transfer or transfection of genes, finding suitable gene thera...